Jonathan Paul Miller was born on July 27, 1975 in Warren, Ohio to John and Carol Miller. He attended Yale University where he graduated in 1998 with a B.S. degree. He then attended Case Western Reserve University in Cleveland, Ohio where, in 2002, he was elected to Alpha Omega Alpha and received his M.D. degree. He carried out his neurosurgical training at Case Western Reserve University and University Hospitals of Cleveland, and subspecialty training in Functional and Stereotactic Neurosurgery at Oregon Health & Science University in Portland, Oregon.

Dr. Miller joined the Department of Neurological Surgery at University Hospitals of Cleveland/Case Western Reserve University in 2008 as an Assistant Professor and was promoted to Associate Professor in 2014 and Professor in 2018. In 2013, he was named inaugural George R. and Constance P. Lincoln Endowed Chair and Director of the Functional and Restorative Neurosurgery Center at University Hospitals. In 2015, was appointed Vice Chair of Educational Affairs and Associate Residency Program Director of the Department of Neurological Surgery.

He is a Fellow of the American College of Surgeons and has served on the Board of Directors of the American Society of Stereotactic and Functional Neurosurgeons, Board of Directors of the Functional Neurosurgery Society, Executive Council of the AANS/CNS Joint Section on Pain, Secretary of the Ohio State Neurosurgical Society, and Associate Editor of the journal Neurosurgery. He has served as member of the CNS Scientific Program Committee, NREF Scientific Review and Development Committees, three NIH study sections, and two US Army CDMRP programmatic panels.

Dr. Miller has published over 100 peer-reviewed papers and has received 15 national awards. His clinical and research interests include surgery for epilepsy, movement disorders, chronic pain, and peripheral nerve disorders, as well as development of novel treatments for a variety of disorders using neuromodulation. He has led the surgical team for multiple translational research projects, including the first ever use of an implanted muscle stimulation system controlled by brain-computer interface to allow arm movement in individuals with cervical paraplegia, gene therapy for Alzheimer’s disease, stem cell implantation for ischemic stroke, and deep brain stimulation for tinnitus, hypertension, memory loss, and epilepsy. He holds several patents and invention disclosures related to neuromodulation.

In October of 2001, he married Katie Kristofco. They have twin sons, John and William, born in 2008.